Twitch laying off 35% of staff a year after doing a large layoff does not bode well for Twitch's future especially when you see that Twitch is grabbing every cent possible from streamers (lower commission, trying to get a hand on donations, multiplication of ads...).
Obviously I don't know what it costs to run this delivery network, but one thing I know is that if Twitch is forced to use and pay AWS servers (Amazon is the parent company), then perhaps it's costing them too much compared to their own specialized hardware.
Does not bode well for streamers.
With that said, 90% of streamers have less than 10 viewers so streamers could just as well host their own video servers instead of defaulting to Twitch. That is, until their view count crosses a profitability threshold and Twitch servers become viable.